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HGH Raw Material

  • 101
  • 1g
  • 1800
  • $1600 / g

Details

We allow much discount according to the quantity and ship with very safe package.


[Drug Name]


Common name: injection of recombinant human growth hormone

Product name:

English name: Recombinant Human Growth Hormone for Injection

Major components: recombinant human growth hormone

[Characters]

White lyophilized powder.

[Toxicology]

Recombinant human growth hormone (rhGH) has the same effect with human endogenous growth hormone to stimulate epiphyseal cartilage end cell differentiation, proliferation, stimulate the growth of cartilage matrix cells, stimulate osteoblast differentiation, proliferation, causing linear growth acceleration and bone widens ; promote systemic protein synthesis, corrective surgery after trauma negative nitrogen balance, correcting severe infection and cirrhosis due to hypoalbuminemia; stimulate immunoglobulin synthesis, stimulate the lymphatic tissue, macrophages and lymphocytes proliferation, enhanced resistance to infection; stimulate collagen burn wounds and surgical incisions fibroblast cells, macrophages proliferate and accelerate wound healing; promote myocardial protein synthesis, increased myocardial contractility, reduced myocardial oxygen consumption, regulate fat metabolism, lower serum cholesterol, low-density lipoprotein levels; supplement inadequate or lack of growth hormone, regulating fat metabolism in adults, bone metabolism, heart and kidney function.

[Pharmacokinetics]

As noted in the literature, the same effect of subcutaneous or intramuscular injection administered in two ways, subcutaneous injection is usually higher than intramuscular injection can lead to higher concentrations of serum GH, IGF-1 concentrations but produced but it is consistent. GH is usually slower absorption, plasma GH concentration generally within 3 to 5 hours after the administration and reached the peak; elimination half-life is generally 2 to 3 hours, GH clearance by the liver and kidney, and adult children faster directly from the urine is not excluded GH extremely trace through metabolism.

[Indications]

For endogenous growth hormone deficiency, Turner's syndrome and chronic renal failure due to slow growth of children and the treatment of severe burns.

[Dosage]

1ml of water for injection before use along the sides of the bottle slowly adding the lyophilized rhGH, a slight turn to make it all dissolved shake, do not shake vigorously.

The dose used to promote children's growth vary, the recommended dose is 0.1 ~ 0.15IU / kg body weight / day, daily, subcutaneous injection, treatment for three months to three years, or as directed.

For the treatment of severe burns recommended dose is 0.2 ~ 0.4IU / kg body weight / day, daily, subcutaneous injection, treatment is usually about two weeks.

[Adverse reactions]

Growth hormone can cause a transient hyperglycemia, often with prolonged treatment or after stopping back to normal.

Approximately 1% in clinical trials of children with short stature have side effects, the symptoms of common transient local injection site reactions (pain, tingling, swelling, etc.) and fluid retention (peripheral edema, arthralgia or myalgia), these side effects occur earlier, but the incidence decreased with treatment time, rare affect daily activities.

Cause long-term injection of recombinant human growth hormone in vivo antibody production in a small number of patients, low antibody binding force, no exact clinical significance. But if the results failed to meet the expected growth, it may have antibodies, antibody binding force exceeds 2mg / L, it may affect the efficacy.

[Taboo]

1 epiphyseal closure of children disabled.

2. tumor progression in patients with disabling symptoms.

3 severe systemic infections in critically ill patients with acute disabled in the body during shock.

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